When to Start Progesterone After Ovulation

If you are struggling to conceive, you may soon realize just how many things have to go perfectly right in order for you to get that successful pregnancy. Progesterone is an important sex hormone that plays a vital role in preparing your body for pregnancy. If you have gone through fertility treatment, you have likely been prescribed progesterone medication to take during your cycle. This may be your first time taking it or you may just be curious about progesterone in general. This blog post will delve into the basics of progesterone and when to start progesterone after ovulation.

Being one of the main hormones in women, progesterone is a natural hormone primarily responsible for regulating your menstrual cycle. It helps to build a thick uterine lining so that fertilized egg can implant itself successfully after travelling down the fallopian tube. Without progesterone, the thick lining may not develop adequately. This can result in difficulties with getting pregnant or maintaining a developing embryo. Read on to learn more about progesterone and its role in conception.

This article is for informational purposes only and does not give medical advice.  Always check with your healthcare provider with any questions or concerns you may have.

What is Progesterone?

Progesterone is a hormone that is naturally produced in the ovaries after ovulation occurs. The main function is to prepare and maintain the uterus for pregnancy. It does this by thickening the lining of the uterus, known as the endometrium, to make it more receptive to a fertilized egg.

During the follicular phase, estrogen is the dominant hormone and causes the lining of the uterus to thicken.  Estrogen levels will continue to rise, causing the cervical mucus to become thinner and more hospitable for sperm.

A dominant follicle will then release an egg during ovulation, and the remaining follicular cells will form the corpus luteum to begin producing progesterone. If pregnancy does not occur, the corpus luteum will eventually break down, causing progesterone levels to decrease and triggering a menstrual period.

After ovulation, the progesterone takes over as the dominant hormone and plays an important role in continuing to thicken the lining in preparation for a potential pregnancy. 

If pregnancy does not occur, the level of progesterone drops, leading to shedding of the uterine lining and menstruation. If pregnancy does occur, progesterone levels remain high to support the growing embryo and maintain a healthy pregnancy.

The peak progesterone level is usually reached about seven days after ovulation, and then starts to decrease if pregnancy does not occur.

During a standard 28 day menstrual cycle, progesterone levels rise after ovulation and peak around cycle day 21.  This process repeats itself every month unless pregnancy occurs. If you have an ovulatory condition, such as Polycystic ovary syndrome (PCOS), you may not have regular cycles.  This condtion comes with hormonal imbalances and can make it harder to pinpoint ovulation.

The adrenal glands and placenta also produce small amounts of progesterone. During pregnancy, the placenta takes over the production of progesterone to support the growing embryo.  The progesterone will remain elevated until the end of pregnancy, and then drop significantly after childbirth.

While progesterone is essential for preparing the body for pregnancy, it also has other important functions in both men and women. In men, progesterone helps to produce sperm and maintain a healthy libido. In women, it can help reduce symptoms of PMS and menopause, as well as regulate menstrual cycles. Progesterone is a very important hormone for both fertility and overall health. 

A pair of hands rests on a black laptop.  A red crocheted uterus is next to the laptop and a potted plant on it's side.

How is Progesterone Used in Fertility Treatment?

In the world of reproductive medicine, progesterone support is often prescribed to support the uterus during the first trimester of pregnancy. This extra supplementation of progesterone can help prevent miscarriage and early pregnancy loss. It can also be used to thicken the uterine lining for better implantation of an embryo during in-vitro fertilization (IVF) treatments.  Your healthcare provider will likely do a progesterone blood test after ovulation to make sure you have enough progesterone to sustain a pregnancy.

Progesterone supplements can be taken orally, vaginally, or through injections. Each method has its own benefits and your doctor will determine the best route for you based on your specific situation. 

Progesterone injections are typically used for those undergoing IVF treatments, while vaginal suppositories are more commonly used for intrauterine insemination (IUI) cycles or other types of fertility treatment. Oral progesterone may also be prescribed but may not be as effective as the other methods.

Women with Polycystic Ovarian Syndrome may also be prescribed progesterone to help regulate their menstrual cycles and induce ovulation. PCOS causes low levels of progesterone and can lead to irregular periods or difficulty conceiving. Supplementing with progesterone can help improve fertility for some women.

Progesterone can also be helpful for those with a short luteal phase.  A luteal phase defect is when the second half of the menstrual cycle (the luteal phase) is shorter than normal, leading to difficulties with implantation and maintaining a pregnancy. Progesterone supplementation can help lengthen the luteal phase and improve chances of pregnancy.

There are a variety of ways progesterone can be used to help support your fertility journey. Always check with your doctor to see which method and dosage is best for your situation.

Symptoms of Low Progesterone Levels

If you ever suspect you may have low progesterone levels, you can undergo progesterone testing.  This typically involves a blood sample to measure the levels of progesterone in your body. It is usually done during the second half of your cycle, as this is when the blood progesterone levels should be highest. If test results show you have a lack of progesterone, you may be prescribed a supplement to help increase your progesterone to normal levels.

There are a few low progesterone symptoms and signs to be aware of. These include:

  • Irregular cycles or absent periods
  • Difficulty conceiving
  • Recurrent pregnancy loss 
  • Spotting mid-cycle or during pregnancy
  • Luteal phase deficiency
  • If you are tracking your basal body temperature, you may notice lower temperatures in the second half of the cycle after ovulation.  You may also see a short luteal phase or a dip in temperature after ovulation.

If you experience any of these symptoms, talk to your health care provider about checking your hormone levels, including progesterone.

When to Start Progesterone After Ovulation?

If you are taking progesterone during your fertility treatment, it is important to know when to start taking it after ovulation. This timing can vary depending on your specific treatment protocol and your doctor’s recommendations. Progesterone is a very important pregnancy hormone and plays a key role in supporting a healthy pregnancy.

For those undergoing an IVF cycle, progesterone injections are typically started within a day or two after egg retrieval.  It is then continued after the embryo transfer and through the first weeks of pregnancy. Vaginal suppositories may also be started at this time or a few days later, depending on the specific medication regimen. The suppositories are typically stopped at the end of the first trimester, unless otherwise specified by your healthcare provider.

If you are taking progesterone for a natural cycle or IUI cycle, it may be started around the time of ovulation or soon after. Your doctor will monitor your hormone levels and adjust the timing as necessary.

The amount of progesterone you take can vary, but the usual dose is around 200mg per day. Your doctor may adjust this dose based on your specific needs and hormone levels.

It is important to follow your doctor’s instructions and take your progesterone as prescribed to ensure the best chance of success in your fertility treatment.

Side Effects of Progesterone

If you are taking progesterone supplements, there are a few side effects you should be aware of. 

These can include:

  • Breast tenderness
  • Mood swings or mood changes
  • Bloating and water retention
  • Nausea or vomiting
  • Headaches
  • Hot flashes

As progesterone rises, it can also cause a rise in body temperature. This is why tracking basal body temperature can be helpful when trying to conceive and during fertility treatments.  

These side effects are typically mild and subside as your body gets used to the progesterone. If you experience severe or prolonged side effects, be sure to talk to your doctor.

A female doctor wears a white coat and looks at a computer screen.

What Else Should I Know About Progesterone and Ovulation?

We have covered much of the basic information regarding progesterone and ovulation. Here are a few additional things you should know.   

First, there are some natural ways to increase progesterone levels, such as eating a healthy diet and avoiding stress. Certain supplements, like vitamin B6 and chasteberry (also known as vitex), have also been shown to help boost progesterone levels.

Secondly, if you are trying to track ovulation and fertility signs, it is important to remember that progesterone rises after ovulation, not before. This means that signs like fertile cervical mucus and a positive ovulation test indicate impending ovulation, not that it has already occurred.

A home pregnancy test works by picking up the pregnancy hormone human chorionic gonadotropin (HCG).  A pregnancy test will not pick up progesterone, so will not be able to tell you if you have low or high levels of progesterone.

If you are taking an oral contraceptive, it is important to note that this will suppress ovulation and therefore, natural progesterone production. Birth control pills can lead to lower levels of progesterone in your body.  When you stop taking them, your normal progesterone levels will return, though it may take a couple of cycles.

In an ectopic pregnancy, progesterone levels may be lower than expected for a normal pregnancy. Your doctor will monitor your hormone levels closely and take any necessary actions to treat this type of pregnancy.

High progesterone levels can also be a sign of a multiple pregnancy (twins, triplets, etc.). If you are undergoing fertility treatments and have higher than normal progesterone levels, it may indicate a potential multiple pregnancy.  Your doctor will monitor this closely and make any necessary adjustments to your treatment plan.

Lastly, if you are undergoing fertility treatments and taking progesterone supplements, it is important to continue taking them until instructed by your doctor. Suddenly stopping progesterone can cause a drop in hormone levels and potentially lead to a miscarriage. Always follow your doctor’s instructions and communicate any concerns or questions you may have.

Overall, progesterone plays a crucial role in ovulation and fertility. Low levels can lead to difficulties with conceiving and maintaining a pregnancy, but supplementing with progesterone can potentially help increase chances of success. 

Progesterone plays an essential role in preparing and maintaining the uterus for pregnancy. In fertility treatment, it is often prescribed to support a healthy pregnancy and improve chances of conception. Knowing when to start progesterone after ovulation is crucial for successful treatment. If you have any concerns about your progesterone levels, talk to your doctor for personalized recommendations. Remember, every fertility journey is unique and your doctor will work with you to create the best treatment plan for your individual needs. Stay informed and empowered throughout your treatment process, and do not be afraid to ask questions or voice any concerns you may have. 

Pin for Later!

When to Start Progesterone After Ovulation Pin

Leave a Reply